CV Lattes
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Universidade Estadual de Campinas (UNICAMP). Instituto de Biologia (IB) (Institutional affiliation for the last research proposal) Birthplace: Brazil
"Dr. Henrique Marques-Souza is an assistant Professor of the Department of Biochemistry and Tissue Biology at the University of Campinas - UNICAMP. He is an Agricultural Engineer by the University of Londrina, Master in Sciences by the Center of Nuclear Energy in Agriculture, of the University of São Paulo and Ph.D. by the University of Cologne, Germany. Prof. Marques-Souza did a postdoc at the University of California, Berkeley, as a Research Associate of the Howard Hughes Medical Institute. His carrier has been dedicated to understand the role of gene regulatory networks controlling cell fate decisions in animal development and regeneration by the use of technologies such as RNAi interference, Genome Editing (CRISPR-Cas9) and transcriptome analysis. Currently, the main focus of Prof. Marques-Souza's lab is to develop biotechnological solutions to control agricultural pests and diseases." (Source: Lattes Curriculum)
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Food production in the world is reduced by about 30 to 40 due to pests and diseases, resulting in about US430 billions loss. The most frequently used control methods are chemical molecules that result in unwanted consequences such as pest and pathogen resistance against the molecules, environmental consequences and negative impact in human and other animal' health. RNAi-based pest control…
Gene regulatory Networks (GRN) controlled by transcription factors are the main molecular component acting on the maintenance or alteration of cell states. Among the GRNs described so far, the GRN controlling heart development is of great interest, due to its potential application for human health. The role of many genes and gene interactions have been characterized during cardiac differe…
Agribusiness occupies a highly significant position in the political-economic-social interests in Brazil. One of the great challenges of agriculture is the constant threat of production losses due to biotic (pests, diseases, and weeds) and abiotic stresses (drought, frost, nutrition, among others), which cause damage to various crops, such as corn, soybeans, beans, potatoes, among others.…
Gene silencing through RNAi has revolutionized the study of gene function, particularly in non-model insects and as yet unsequenced species genomes, which is the case for most agricultural pests today. One of the most important steps for the development of RNAi technology for the control of agricultural pests and diseases is the choice of the target gene. In this context, a transcriptome …
The embryoid polarity of the embryo has a fundamental role in the embryonic axis determination, in a way that it generates a differential signalling in embryo regions during its development, allowing the definition of different cell populations. The definition of those axes depends on several signalling pathways. One of those is the Wnt/²-catenin signalling pathway, which is essential to …
One of the mysteries in studying the differentiation of CTE as a model for embryonic development is the phenomenon of generating, in vitro, cells and embryonic tissues without signaling located of extraembryonic tissues, essential for the development of the embryo, and morphogenetic movements of gastrulation that culminate in origin and spatial distribution of the three germ layers; ectod…
The aims proposed in the Young Researcher project address the regulation of gene expression of several transcription factors by Coup-TFII, to understand the molecular basis of embryonic cell differentiation. Once obtained at different modulation conditions of COUP-TFII expression, the embryoid bodies will be analyzed for the expression of tissue-specific gene markers and potential targets…
(Only some records are available in English at this moment)
The capacity of cells to change its molecular and morphological characteristics upon stimuli and generate specific cell types is one of the most intriguing phenomena studied in modern biology. Embryonic stem cells (ESC) are on the center of this research due to its capacity to change from an apparently homogenous population of cells into embryoid bodies containing representatives of all t…
| 1 / 1 | Ongoing research grants |
| 2 / 1 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 7 / 4 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 13 / 9 | All research grants and scholarships |
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