Abstract
When exposed on the outer leaflet of the plasmatic membrane, phosphatidylserine (PS) has an important role in the removal of apoptotic cells by the macrophage without a inflammatory response. It was proposed that Leishmania used the process to be phagocited by the macrophage. Efforts to obtain a knock-out Leishmania for phosphatidylserine synthesis did not result in the expected mutant, i…