Abstract
Supplementation of bone substitutes with recombinant platelet-derived growth factor-BB (PDGF-BB) can enhance bone regeneration. The aim of the study was to evaluate the effect of PDGF-BB on bone formation in the presence of ²- tricalcium phosphate and bovine bone mineral matrix in a rat calvaria defect model. The authors examined 5 mm rat calvarial defects treated with ²-tricalcium phosph…