CV Lattes
ResearcherID
ORCID
Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. Escola Paulista de Medicina (EPM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Dr. Briones received his BSc-MSc from the University of São Paulo, his PhD from the Federal University of São Paulo (1994) and a postdoctoral fellowship from New York University (1994-1996). He is a professor at the Federal University of São Paulo since 1996 and an international research scholar of the Howard Hughes Medical Institute (USA) (2000-2005). He has experience in #8203;#8203;Genomics and Molecular Biology, with emphasis on evolutionary processes and bioinformatics. He participated as a principal investigator of the Xylella fastidiosa genome project-FAPESP, was a coordinator of the sequencing center in the human cancer genome project (FAPESP and Ludwig Institute) and the epileptic brain transcriptome. He is a full member of the Academy of Sciences of the State of São Paulo, Life Fellow of the Galton Institute (United Kingdom), was a member of the steering committee of the Brazilian initiative on precision medicine (BIPMED). He is associate editor in bioinformatics and computational biology of Frontiers in Genetics and coordinator of the Center for Medical Bioinformatics at Escola Paulista de Medicina, Federal University of São Paulo. He was awarded the "DASA-Veja Saúde" of inovation in Medicine in the Genomics category is a full member of Sigma Xi, The Scientific Research Honor Society. (Source: Lattes Curriculum)
| News published in Agência FAPESP Newsletter about the researcher |
| More itemsLess items |
| TITULO |
| Articles published in other media outlets ( ): |
| More itemsLess items |
| VEICULO: TITULO (DATA) |
| VEICULO: TITULO (DATA) |
This research proposal consists of a "spin-off" project based on volunteer samples of the Oxford-UNIFESP ChAdOx1 nCoV-19 vaccine trial. The proposal will involve the 1,000 volunteer samples, and corresponding time points, to primarily establish a repository for the whole academic community of the São Paulo State. This repository will be converted in a Biobank after the project is conclude…
The goal of this proposal is to answer the question: How does Candida albicans mitochondria adapt or modulate the fungal adaptation to sudden growth condition shifts such as decreased oxygen concentration and increased temperature often associated with hospital-acquired infections? In other words, we aim to characterize the microadaptative response of Candida albicans mitochondria in low …
Haematogenic infections caused by Candida albicans in hospitalized patients are of great impact in worldwide public health in terms of morbidity and mortality. Recent progress on the development of antifungal drugs has not reduced the lethality of candidaemia which is still approximately 40 to 50% of infected patients. The objectives of this project are therefore (1) to improve diagnostic…
The aim of this project is to validate the structure and to define the sequences for at least 2,000 full-length human genes in a two-year period. As opposed to conventional full-length cDNA sequencing projects such as MGC, gene structure will be predicted and validated without the construction of highly elaborated cDNA libraries or full length transcript determination. Gene sequences will…
(Only some records are available in English at this moment)
This proposal is part of the ongoing FAPESP thematic project (20/08943-5). The PD fellow will work directly in Subprojects 3 and 5 described below. The thematic project consists of the deployment of the international project with 2.000 samples of volunteers from the Oxford-UNIFESP test of the ChAdOx1 nCoV-19 vaccine. The objective is to establish a repository for the entire academic commu…
This project aims to study the effects of the concomitant reduction of oxygen tension and temperature increase in the mitochondrial genome of the pathogenic yeast Candida albicans, concerning variations in its topology, number of copies, integrity and nucleotide sequence. In nosocomial infections, the patient is often infected by yeasts present on abiotic surfaces such as catheters. Yeast…
(Only some records are available in English at this moment)
Amyotrophic lateral sclerosis (ALS) is the third most common neurodegenerative disease and the most common, adult-onset, motor neuron disease. About 10% ALS is the familial form in which 15-20% of cases are ALS1, associated with mutations in superoxide dismutase 1 (SOD1) gene. Nine genes are known to carry ALS-causing mutations and 13 others are implicated in ALS pathogenesis. These 22 ge…
| 1 / 1 | Ongoing grants |
| 11 / 5 | Completed research grants |
| 13 / 4 | Completed scholarships in Brazil |
| 2 / 1 | Completed scholarships abroad |
| 27 / 11 | All research grants and scholarships |
| Associated processes | |