CV Lattes
ResearcherID
ORCID
Google Scholar Citations
Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas (FCF) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduated in Pharmacy and Biochemistry from the University of São Paulo (1985), master's (1990) and doctorate (1996) in Pharmacology from the University of São Paulo. Since 2014, is Associate Professor in the Department of Clinical Analysis and Toxicological of the School of Pharmaceutical Sciences, University of São Paulo. Has experience in the area of neurodegeneration, such as Alzheimer's disease, oxidative stress. Current research area is on Toxicology, with emphasis on neurotoxicity of cigarette smoke, methylecgonidine (pyrolysis product of cocaine) and in the search for new alternatives for the treatment of substance use disorder. (Source: Lattes Curriculum)
| Articles published in Pesquisa FAPESP Magazine about the researcher: |
| El cronómetro del cerebro |
| The brain’s timepiece |
| More itemsLess items |
| News published in Agência FAPESP Newsletter about the researcher |
| More itemsLess items |
| TITULO |
| Articles published in other media outlets ( ): |
| More itemsLess items |
| VEICULO: TITULO (DATA) |
| VEICULO: TITULO (DATA) |
Psychedelics have received a lot of attention in recent years for the treatment of mental illnesses such as depression, anxiety, and substance use disorder. The use of cocaine is predominantly a problem in South American countries, as its production mainly occurs in Colombia, Bolivia, and Peru, with Brazil being the world's largest crack market. Ayahuasca is a psychedelic brew, with its m…
Cocaine is a psychostimulant alkaloid, being in Brazil and Europe, the second most used illicit drug, with a high potential to induce addiction. Faced with this problem, research on psychedelics has intensified with a focus on the treatment of drug addiction. Psychedelics have a good safety profile, do not induce drug addiction and have low potential to cause tolerance. The most studied p…
Epigenetic are modifications that occur in that are DNA capable of controlling thetranscriptional process. During the egg's implantation phase, DNA is more vulnerable toexternal influences such as cigarette smoke, increasing the risk of retardation of fetaldevelopment, risk of postnatal sudden death and abnormalities of the immune system.Moreover, children of mothers who smoke develop ast…
Neurotoxicity has been defined as any adverse effect on the structure and function of the nervous system. Thus, the aim of this study is to evaluate the effects of environmental tobacco smoke (ETS) in vivo and the effects of anhydroecgonine methyl ester (AEME) in vitro. The focus of the ETS part is synaptic plasticity and the endocannabinoid system. Mice C57/BL will be exposed to a mixtur…
(Only some records are available in English at this moment)
Psychedelics have gained prominence in recent years in the treatment of mental disorders such as depression, anxiety and substance use disorders. The use of cocaine, widely produced in South America, especially in Colombia, Bolivia and Peru, represents a major public health problem, with Brazil being the main crack market in the world. Harmine, one of the main compounds in ayahuasca, reve…
Ayahuasca is a psychedelic beverage traditionally used in rituals and therapies by indigenous groups in the Amazon, composed of N,N-dimethyltryptamine (DMT) and ¿-carbolines, such as harmine (HRM). The ¿-carbolines are reversible inhibitors of monoamine oxidase A (MAO-A), allowing DMT to be absorbed and distributed to the central nervous system. Fluoxetine (FL), prescribed for the treatme…
Ayahuasca is a psychoactive drink commonly used by people from the Amazon region, its main active principles being N,N-dimethyltryptamine and beta-carbolines, harmine, harmaline, and tetrahydroharmine. Several studies explore the potential therapeutic use of psychedelic substances for treating mental disorders such as substance use. However, most of these studies focus on ethanol and toba…
Ketamine is an anesthetic commonly used illegally by adolescents and young adults in parties and raves, due to the fact that it presents psychotropic actions which intensifies social interaction. Ethanol, on the other hand, is a legal substance and its consumption is socially accepted, which can facilitate its abusive use, as well as the association with other substances, such as ketamine…
Cocaine (COC), a drug derived from coca leaves (Erythroxylon coca) is found in two chemical forms for use: cocaine hydrochloride, known as "powder", used intranasally or intravenously, and the base form, known as Crack, used through smoke. The process of burning the crack stones generates a product called anhydroecgonine methyl ester (AEME), which is inhaled along with the volatilized coc…
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing grants |
| 13 / 9 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 26 / 17 | Completed scholarships in Brazil |
| 1 / 0 | Completed scholarships abroad |
| 43 / 29 | All research grants and scholarships |
| Associated processes | |