CV Lattes
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Faculdade de Ciências da Saúde de Barretos Dr Paulo Prata (FACISB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Ciências Biológicas from Universidade Estadual Paulista Júlio de Mesquita Filho (2006), master's at Pathological Anatomy and Clinical Pathology from Universidade Estadual Paulista Júlio de Mesquita Filho (2009) and doctorate at Pathological Anatomy and Clinical Pathology from Universidade Estadual Paulista Júlio de Mesquita Filho (2011). Has experience in Probability and Statistics, focusing on Data Analyses, acting on the following subjects: breast cancer, cellular proliferation, mate, whole mounts and lemongrass. (Source: Lattes Curriculum)
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Despite constant advances in cancer treatment, some tumor types continue to have very low morbidity and mortality. The Cancer Genome Atlas (TCGA) consortium has contributed to the identification of genomic and genetic alterations in several tumors. The extensive scientific production resulting from this program has, in general, found tumor subtypes that may be more (or less) resistant to …
Gliomas are the most frequent and malignant brain neoplasias among the central nervous system tumors. Some subtypes are incurable neoplasias, with mean survival of 13 months, and less than 2% of the patients reach 5 years post treatment. The low success in the treatment of these tumors is, in part, due to the lowunderstanding of their molecular bases. Moreover, our research group describe…
Cervical cancer is mainly caused by persistent high-risk HPV infection. However, the mechanisms associated with the clearance or persistence of HPV infection remain poorly understood and appear to be multifactorial, with possible protective factors of the lactobacillary microbiota being associated. Therefore, the present study aims to characterize the vaginal microbiota of women with high…
Cervical cancer is mainly caused by persistent high-risk HPV infection. However, the mechanisms associated with the clearance or persistence of HPV infection remain poorly understood and appear to be multifactorial, with possible protective factors of the lactobacillary microbiota being associated. Therefore, the present project aims to characterize the vaginal microbiota of women with pr…
Despite advances in molecular discoveries of Glioblastomas (GBM) IDH wild type, treatment success is reserved, with the use of the same standard therapy for all patients. Our research group described a signature of 12 genes associated with patients diagnosed with GBM with low survival, and CTSL proved to be important in several in silico analyses. Other articles show the high expression o…
The alarming data associated with sexually transmitted infections (STIs) in Brasil make them a relevant public health issue. The persistent infection by oncogenic high-risk Human Papillomavirus (HPV) genotypes overly increase the chances of development of precursor lesions of the cervix, which, if untreated, can evolve to invasive squamous cell carcinoma. There are some factors associated…
Our research group found loss in regions of the short arm of chromosome 9 in a high percentage of patients diagnosed with glioma, where the MTAP gene is present. This gene encodes an enzyme essential for the recycling processes of adenine and methionine formed during the degradation of nucleotides. Studies have shown that the administration of MTA, a substrate of MTAP, has attenuated the …
Gliomas are the most frequent and malignant brain tumors among the central nervous system neoplasms. Among glial types, glioblastomas (GBMs) are incurable, with an average survival of approximately 13 months, and less than 2% of patients reach 5 years after treatment. The low success rate in these tumors is due in part to the low understanding of their molecular basis. In 2016 our researc…
(Only some records are available in English at this moment)
Gliomas are the most frequent and malignant tumors within the Central System Nervous (CNS) tumors. They are an incurable neoplasia, with a survival average of approximately 13 months, and less than 2% of the patients survive 5 years after the treatment. The low success in the treatment of these tumors is, in part, due to the low understanding of their molecular bases. The present project …
| 2 / 2 | Completed research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 9 / 7 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 15 / 13 | All research grants and scholarships |
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