CV Lattes
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Universidade Estadual de Campinas (UNICAMP). Faculdade de Ciências Aplicadas (FCA) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Nutrição from Universidade José do Rosário Vellano (2001), master's at Nutrition from Universidade Federal de Viçosa (2003) and doctorate at Clinical Medicine from Universidade Estadual de Campinas (2008). Has experience in Medicine, acting on the following subjects: nutrigenômica, obesidade, sinalização celular, inflamação and diabetes. (Source: Lattes Curriculum)
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Obesity advances worldwide in an uncontrolled way, being considered a predisposing factor also to neurodegenerative diseases such as Alzheimer's Disease (AD). Not only the senescence is involved in the pathogenesis of AD, but also the inflammatory process characteristic of the obesogenesis, which can anticipate its onset and even be an initial trigger. Hippocampal neuroinflammation can pr…
Obesity is currently the most important public health problems and has been considered a disease out of control. In association, a constellation of diseases such as insulin resistance, hypertension, dyslipidemia, atherosclerosis, and, among others, some types of cancers, are responsible for high rates of mortality or functional disability. These diseases show a common factor, the phenomen…
Omega-3 fatty acids are essential once they are not endogenously synthesized in mammals, and their dietary intake is mandatory. These lipids are essential because they act as substrates for several secondary chemical mediators, membranes, organelles, and tissue constituents. The ±-linolenic acid (ALA - C18:3) is abundantly found in oil from seeds such as chia and linseed, however, its end…
Omega-3 fatty acids (É3) are essential for mammals, necessitating their acquisition through diet. Alpha-linolenic acid (ALA) is found in flaxseed and can be bioconverted, in both animals and humans, to eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), crucial for health. However, this process has low efficiency, making the intake of EPA and DHA from their sources (fish oil) esse…
In the past few decades, several modifiable lifestyle risk factors for dementia have been recognized, such as obesity, physical inactivity, and imbalanced nutrition. Therefore, by investigating the early onsets of neuropathology with different exercise regimens and/or with different nutraceutical ingestion using a metabolic disrupted animal model, the scientific community will be closer t…
Nutritional status is a key determinant of central nervous system (CNS) development. Most studies point to the deleterious impact of malnutrition, however, the impact of overnutrition is also a warning. The low-grade inflammatory process associated with obesity can alter the overall permeability of organic biological barriers, among them the blood-brain barrier (BBB). Inflammation inducin…
The protective effects of omega 3 fatty acids (É3) have been the subject of studies for decades. Studies have shown that É3 has an effect on the reduction of inflammatory frames, on the reduction of platelet aggregation, on the improvement of insulin sensitivity, on the immune system, among others. Among the mechanisms by which É3 acts, the activation of the GPR120 receptor shows to be im…
The relationship between the trinomial obesity-asthma-diabetes has increasingly been evidenced by clinical studies. Certainly, it happens due to the pandemic evolution and uncontrolled increasing of obesity worldwide, however, without a clear explanation of the underlying mechanism. Chronic and low-grade inflammation is one of the common denominators present in the genesis of the triad al…
(Only some records are available in English at this moment)
Omega-3 (w3) and omega-6 (w6) are essential fatty acids for mammals and need to be acquired from foods. In vegetable oils, the w6 and w3 species are found as linoleic (C18:2) and alpha-linolenic (C18:3) fatty acids, respectively. Both fatty acids can be endogenously bioconverted in a more biologically active and functional longer species such as the arachidonic (C20:4 [w6]) and eicosapent…
Sepsis is defined as an overactive response to infection, and can progress to septic shock, multiple organ failure and death. Characteristic of sepsis is a systemic reprogramming of glucose and lipid metabolism. Preliminary data generated by the Wang, Perry, and Cintra labs demonstrates that this metabolic reprogramming is a conserved feature of type I inflammation and is crucial to survi…
Diabetes mellitus has reached epidemic proportions in recent decades and constitutes one of the greatest challenges of today's health systems. Type 2 diabetes mellitus (DM2) results from insulin resistance, a phenomenon closely associated with chronic and low grade inflammation, characteristic of obesity. The obesogenic process leads to a myriad of metabolic disorders, which significantly…
| 7 / 3 | Completed research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 10 / 8 | Completed scholarships in Brazil |
| 3 / 3 | Completed scholarships abroad |
| 23 / 17 | All research grants and scholarships |
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