João Alberto Negrão

• Abstract

  Dairy animals are subjected to management and environmental challenges considered stressful that can decrease milk yield, however the effect of stress in apoptosis rate in mammary cells and lactation persistence is unknown. For this reason, understanding the effect of heat stress on molecular pathways related to milk synthesis, oxidation process, proliferation and apoptosis rate in mammar…

  Milk yield in Saanen goats: relationships between stress, expression of genes related to milk synthesis, antioxidant enzymes and heat shock proteins in the mammary gland, AP.R

• Abstract

  The decreasing of milk yield caused by stress has been related to cellular changes and apoptosis in the mammary gland, modulated by action cortisol, insulin, prolactin (PRL), growth hormone (GH) and insulin-like growth factor 1 (IGF-1). By other way, some authors suggest that chaperones can interact with the cellular receptors of cortisol, PRL, GH, insulin and IGF-1 in other tissues, play…

  Milk yield in Saanen goats: relationships between milk synthesis, stress, apoptosis and gene expression in mammary gland, AP.R

• Abstract

  Milk yield in Saanen goats: relationships between stress, cortisol, IGF-I and apoptosis.The increase in milk yield is related to number and activity of epithelial cells. Consequently, the decline in milk production after peak lactation occurs due to a decrease in the secretion activity of epithelial cells, and reduction in the numbers of these cells by apoptosis. It seems that greater lac…

  Milk yield by Saanen Goats: relationship between stress, apoptose, cortisol and IGF-I, AP.R

(Only some records are available in English at this moment)

• Assessment of antioxidant potential lemongrass (Cymbopogon citratus (D.C.) Stapf) on the apoptosis of tissue mammary and milk quality of Saanen goats, BP.MS

• Abstract

  At the end of 2018, the project "Dairy production in Saanen goats: relationships between milk synthesis, stress, apoptosis and gene expression in the mammary gland" was submitted and approved by FAPESP (Process 2018 / 09093-5). This project aims to study how cortisol (CORT, a universal indicator of stress) and heat chock proteins (HSPs), modulate the interaction between insulin (INS), pro…

  Relationship between milk synthesis, stress and expression of HSPs (heat chock proteins) in the mammary gland of Saanen goats, BE.PQ