Abstract
The flaviviruses transmitted by mosquitoes cause a variety of diseases, including fevers, encephalitis and hemorrhagic fevers. The Rocio virus (ROCV) is a member of Japanese encephalitis virus serocomplex and has caused fatal encephalitis in various cities in the São Paulo state-Brazil, between the years 1975-1977. The envelope (E) glycoprotein is the major component of the virion externa…