Undergraduate degree in Health Sciences from Universidade de São Paulo ( USP -2014) and doctorate degree in Microbiology and Immunology from Universidade Federal de São Paulo (UNIFESP - 2019). (Source: Lattes Curriculum)
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Despite being a growth factor, Fibroblast Growth Factor (FGF) 2 has anti-proliferative and anti-tumor activities in some contexts. In adrenocortical mouse (Y1) lineage, FGF-2 delays S-phase progression and permanently blocks cells in the G2/M transition of the cell cycle, leading them to senescence. This project is the continuation of previous project (2015/04867-4) (carried out for 1 yea…
Some nuclear proteins are essential for the maintenance and regulation of the genome, transforming extracellular and intracellular signals into changes in gene expression and phenotype. In this project, we aim to analyze the nuclear proteome at different phases of the cell cycle and senescence of mouse tumor cells stimulated with FGF2. To this end, nuclear extracts will be systematically …
Despite being a growth factor, FGF-2 has anti-proliferative and tumor suppressive functions in some cellular contexts. In a murine adrenocortical tumor cell line (lineage Y1), FGF-2 triggers an initial mitogenic response through ERK1/2, PKC and AKT signaling but results in a G2/M cell cycle arrest through RhoA/GTP-src signaling. Recently, we found transcription factors related to early-ge…
| 3 / 2 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 4 / 3 | All Scholarships |
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CV Lattes
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