Abstract
Background and objectives: Sickle Cell Disease (SCD) is a generic term used to determine a group of genetic alterations characterized by hemoglobin S (Hb S) predominance. Sickle cell anaemia (SCA), the most common and severe SCD, is an autosomal recessive, inherited disorder of hemoglobin structure caused by a point mutation in the Beta²-globin chain of hemoglobin. Low blood oxygenation p…