CV Lattes
Universidade de São Paulo (USP). Instituto de Química (IQ) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Has a bachelor degree of Veterinary Medicine by São Paulo University (FMVZ-USP). Developed two years of scientific research looking at novel therapeutic targets regulated by NF-kB in KRAS driven lung cancer at Cancer Molecular Biology Laboratory (LBMC) at Institute of Chemistry at São Paulo University (IQ-USP). Got her PhD in the Integrated Cancer Research Laboratory (LAPIC) at the same institute, where developed a research with long non-coding RNAs regulated by K-Ras oncogene in pancreatic cancer. (Source: Lattes Curriculum)
| News published in Agência FAPESP Newsletter about the researcher |
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Activating mutations in KRAS are very frequent in Pancreatic Ductal Adenocarcinomas (PDACs), but different approaches to directly target Ras for therapy failed in clinical trials. An alternative route for blocking RAS-driven oncogenic pathways is to target downstream effectors of RAS involved in promoting the oncogenic phenotype. Long non-coding RNAs (lncRNAs) regulate gene expression thr…
Given that the NF-kB subunit p65 plays an important role in oncogenic Ras-induced neoplastic transformation, including K-Ras-induced lung transformation, it is crucial to identify p65-regulated genes that promote oncogenesis. Based on the hypothesis that p65 regulates potential therapeutic targets in the lung, our experimental approach will include identification of differentially express…
Given that the NF-kB subunit p65 plays an important role in oncogenic Ras-induced neoplastic transformation, including K-Ras-induced lung transformation, it is crucial to identify p65-regulated genes that promote oncogenesis. Based on the hypothesis that p65 regulates potential therapeutic targets in the lung, our experimental approach will include identification of differentially express…
| 3 / 3 | Completed scholarships in Brazil |
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