Has experience in General Biology, focusing on General Biology (Source: Lattes Curriculum)
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The use of organic components is a new approach to control dental erosion. Recombinantly produced proteins from sugar cane (CaneCPI-5) and MaquiBerry (MaquiCPI-3) have been shown to protect this tooth wear, as well as a peptide from Estatherin and the use of commercial Hemoglobin. Most of these studies were carried out using in vitro and in situ protocols. However, the development of in v…
Currently, the use of proteins/peptides through acquired pellicle engineering demonstrated protection against dental erosion, using two application vehicles (solution and gel). However, there is a lack of studies with these treatments in in vivo protocols, as well as the absence of studies with another vehicle, for example, orodispersible film. Thus, the objective of this study will be to…
In the first part of the project, carried out at the University of Toronto (BEPE), the design, characterization and evaluation of new resins functionalized with methacrylate-DNA conjugates hybridized with CaneCPI-5-, Stn15pSpS- or Hb-DNA will be carried out. DNA strands will be covalently linked to commercially available methacrylate and to CaneCPI-5, Stn15pSpS or Hb, using standard bioco…
Recently, procedures involving "Acquired Pellicle Engineering" have been proposed as a new strategy for the control of dental erosion. The incorporation of actives into mouthwash solutions or gels could improve the ability of Acquired Enamel Pellicle (AEP) to protect against erosion. Preliminary experiments from our group revealed that CaneCPI-5, a sugarcane protein, was able to protect t…
Polymeric materials, especially composite resins, have been extensively employed and new formulations have been often proposed. Acquired pellicle is a film constituted mainly of salivary proteins of glycoproteins that deposit onto the surfaces that are exposed to the oral environment. However, the composition of the acquired pellicle formed on surfaces of composite resins was never studie…
Dentin, demineralized organic matrix has a protective role against subsequent erosive challenges. However, this layer may be degraded by proteases such as matrix metalloproteinases (MMPs) and cysteine cathepsins (CCs). Recently, the use of matrix protease inhibitors has emerged as an important preventive tool against erosion dentin. However, the exact mechanism by where protease inhibitor…
Recently, studies involving the incorporation of proteins into the acquired pellicle have been proposed as a new strategy for the control of dental erosion. However, probably the greatest challenges in dental erosion research is to find an assessment method that is able analyze dental erosion clinically. Recently, a new hand-held device called Reflectometer Optipen has been developed by P…
| 3 / 3 | Ongoing scholarships in Brazil |
| 3 / 3 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 7 / 7 | All Scholarships |
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