has a Bachelor of Science degree in Biology from State University of Campinas (2003), a Master of Science degree in Genetics and Molecular Biology from State University of Campinas (2006), a Doctor of Philosophy degree in Genetics from Michigan State University (2011), and Post-Doctorate experience in Biochemistry and Molecular Biology from Tampere University, Finland (2013). He has experience in Molecular Biology, Genetics and Biochemistry, specifically in topics related to Mitochondrial Biology, such as: 1) the Use of Alternative Enzimas for the Functional Understanding of the Mitochondrial Respiratory Chain and to Combat Mitochondrial Disorders; and 2) Mitochondrial Genome Structure and Maintenance Mechanisms. He uses and advocate for the use of Drosophila melanogaster as one of the most important model organisms in life sciences research, due to its low culture costs and to the versatility of the molecular genetics tools available. He is currently an Associate Professor at the Department of Biotechnology, College of Agricultural and Veterinary Sciences of Jaboticabal, Sao Paulo State University. (Source: Lattes Curriculum)
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Although the mitochondrial alternative oxidase (AOX) is naturally absent in vertebrates and insects, its xenotopic expression in Drosophila and mammalian models has been shown to combat mitochondrial and related dysfunctions, with potential for its deployment as a human therapy enzyme in the future. AOX is a non-proton pumping, mitochondrial inner membrane enzyme that can bypass respirato…
Although the mitochondrial alternative oxidase (AOX) is naturally absent in vertebrates and insects, its xenotopic expression in Drosophila and mammalian models has been shown to combat mitochondrial and related dysfunctions, with potential for its deployment as a human therapy enzyme in the future. AOX is a non-proton pumping, mitochondrial inner membrane enzyme that can bypass respirato…
Although the mitochondrial alternative oxidase (AOX) is naturally absent in vertebrates and insects, its xenotopic expression in Drosophila and mammalian models has been shown to combat mitochondrial and related dysfunctions, with potential for its deployment as a human therapy enzyme in the future. AOX is a non-proton pumping, mitochondrial inner membrane enzyme that can bypass respirato…
Mitochondria are essential organelles in eukaryotic cells as they are involved in central pathways including energy metabolism and intracellular signaling. Besides being the main cellular site for ATP generation, they are involved in redox signaling, intracellular calcium homeostasis and cell fate after stress. Moreover, they contain their own independent genome. In humans, the mitochondr…
The respiratory chain alternative enzymes constitute additional pathways to the mitochondrial oxidative phosphorylation (OXPHOS) system, in which oxygen consumption is uncoupled from ATP production. The expression of alternative oxidases and alternative NADH dehydrogenases from tunicates and fungi in the fruit fly Drosophila melanogaster, in the mouse and in cultured human cells has prove…
Alternative oxidase (AOX) is a mitochondrial enzyme that catalyzes reactions analogous to those of complexes III and IV, oxidizing coenzyme Q and reducing oxygen. Although it does not contribute to the proton-motive force utilized in ATP synthesis, AOX is capable of maintaining the flow of electrons when complexes III and IV are compromised. Despite its potential therapeutic applications,…
(Only some records are available in English at this moment)
(Only some records are available in English at this moment)
| 3 / 3 | Ongoing grants |
| 2 / 2 | Completed research grants |
| 5 / 5 | Ongoing scholarships in Brazil |
| 23 / 20 | Completed scholarships in Brazil |
| 33 / 30 | All research grants and scholarships |
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CV Lattes
ORCID