Graduate at Bacharelado em Química from Universidade Estadual Paulista Júlio de Mesquita Filho (1984), master's at Biochemistry from Universidade Federal de São Paulo (1988) and PhD. at Biochemistry from Universidade Federal de São Paulo (1994). He was Visiting Professor of the Department of Organic Chemistry, University of Barcelona-Spain (1995), which later developed post-doctoral stage (1996 - 1998). He is currently a full professor at the Institute of Chemistry, Universidade Estadual Paulista Julio de Mesquita Filho. Has experience in Biochemistry, focusing on Chemistry of Macromolecules, acting on the following subjects: peptides, topoisomerases, antibiotics, chromatography, fluorescence and Biomaterials (nanocomposites based on bacterial cellulose for bone regeneration) (Source: Lattes Curriculum)
| Articles published in Pesquisa FAPESP Magazine about the researcher: |
| Imitating bone |
| Mimetismo óseo |
| News published in Agência FAPESP Newsletter about the researcher |
| TITULO |
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The emergence and spread of pathogenic bacterial strains resistant to currently available antimicrobial agents represent the major public health problem in the world. In addition, studies show that by 2050 there will be a significant increase in the number of deaths caused by multiresistant bacterial species and cancer. Given the seriousness of this scenario, it becomes urgent and of grea…
The use of bacterial cellulose has a wide variety of applications due to their physical and chemical properties that give it excellent versatility. In medicine, their multifunctionality include temporary replacement of epithelial tissue in burns cases, ulcers, lesions or grafts, such as artificial blood vessels, as biologic curative for antibiotics and other drugs delivery and acting as a…
(Only some records are available in English at this moment)
Bacterial cellulose is an extremely versatile biopolymer with a wide variety of applications. Due to its considerable mechanical resistance, biocompatibility and high purity, in addition to its nanometric structure, bacterial cellulose can be used in medicine as temporary replacement of epithelial tissue in cases of burns, ulcers, grafts or lesions. In addition to being able to be applied…
The ParD-ParE system represents a toxin-antitoxin module of the broad host range plasmid RK2. ParE (103 amino acids) is the toxin, whereas ParD (83 amino acids) constitutes the antidote able to neutralize ParE by forming a stable complex that is also effective in the autorepression of the parDE operon. The ParE toxin inhibits DNA gyrase activity and thereby blocks DNA replication. Several…
Topoisomerases play a crucial role in DNA replication for both bacterial and human cells, which make them good targets for designing and developing new antibacterial and antitumor drugs. The aim of this project is to design and develop new more potent and selective non-peptide and peptide inhibitors of bacterial and human topoisomerases. Also, metabolic stability is an additional property…
(Only some records are available in English at this moment)
| 13 / 8 | Completed research grants |
| 10 / 6 | Completed scholarships in Brazil |
| 1 / 0 | Completed scholarships abroad |
| 24 / 14 | All research grants and scholarships |
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CV Lattes
ORCID