Abstract
The Myeloproliferative neoplasms (MPN) are diseases characterized by increased proliferation and resistance to apoptosis of mature myeloid lineage cells. The cell lines of Myeloproliferative Neoplasms investigated in this study will be SET-2 and HEL 92.1.7 originated from Polycythemia vera (PV) and essential thrombocythemia (TE) patients and positive for Janus kinase 2 (JAK2) mutation. Th…