CV Lattes
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Universidade Estadual de Campinas (UNICAMP). Instituto de Biologia (IB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduate at Biologia from Universidade Estadual de Campinas (1989), master's at Genetics from Universidade Estadual de Campinas (1992) and ph.d. at Genetics from Universidade Estadual de Campinas (1997). Has experience in Microbiology, acting on the following subjects: pathogenicity, salmonella enterica, genomics and bacterial resistance. (Source: Lattes Curriculum)
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Salmonella enterica is an important animal and human pathogen and its control is essential in the public health. Monitoring the appearance and characteristics of highly pathogenic and more invasive strains is one of the important aspects of this control. In addition, using molecular biology techniques, S. enterica can be attenuated and modified to carry heterologous molecules, with applic…
Previous results from our group indicated that null-mutants of Salmonella enterica for genes encoding Naps (Nucleoid-associated proteins) are attenuated and able to induce protection in the murine model. Data also indicated that some strains presented antitumor properties. Altogether, those results indicate an important biological role of NAPs in S. enterica. Therefore, the general object…
(Only some records are available in English at this moment)
Salmonella enterica Typhimurium is a Gram-negative bacterium belonging to the Enterobacteriaceae family. It is a global public health concern due to its high incidence and severity, causing diseases ranging from gastroenteritis to severe systemic infections. The emergence of multidrug-resistant (MDR) isolates has complicated infection treatment; therefore, it is essential to investigate t…
Bacterial infections are quite common and can rapidly progress to more severe cases such as sepsis and bacteremia. Salmonella sp. is a Gram-negative bacterium that is associated with serious infections in humans and other animals. S. enterica is one of the most prevalent foodborne pathogens, and can cause everything from gastroenteritis to serious systemic infections. The serovars Typhimu…
Infections caused by Staphylococcus aureus represent a significant public health challenge whose history is based on the search for new antibiotics, as this bacterium has constantly acquired resistance to them. In the search for new antimicrobial drugs, violacein, a pigment produced by different species of Gram-negative bacteria, has antimicrobial action against Gram-positive bacteria, pa…
(Only some records are available in English at this moment)
Gram negative bacteria has a complex morphology, composed of a plasma membrane and a cell wall, that are composed of a thin layer of peptidoglycan and a lipopolysaccharide outer membrane, which makes them relatively more resistant to drugs and bactercidal agents. In such context, with the increase in the use of antibiotics, bacteria have developed multidrug resistance. The multidrug resis…
Gram-negative bacteria such as Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, Enterobacter spp., Salmonella and Helicobacter pylori are multiresistant bacteria of clinical interest. Recombinant phage endolysins therefore appear as potential new antimicrobials to combat infections caused by antibiotic-resistant Gram-negative bacteria. Endolysins target the peptidog…
(Only some records are available in English at this moment)
Salmonella spp. is the most significant foodborne pathogen of the Enterobacteriaceae family, capable of infecting both animals and humans. The genus possesses more than 2,600 serovars, and the non-typhoidal (NTF) ones cause salmonellosis, a diarrheic disease that can progress to systemic infections and even lead to death. Annually, several outbreaks of salmonellosis are reported worldwide…
Despite efforts to reduce the levels of pathogens in foods, they persist, causing serious problems in human health and an impacting the economy. The overuse of antibiotics has contributed to the increase of this issue, leading to the emergence of antibiotic-resistant pathogenic bacteria. The wide distribution of Salmonella spp. between animals and its maintenance in food contribute to thi…
Optical molecular imaging (OMI) is a technique developed in molecular imaging based on genomics, proteomics, and modern optical imaging technique, through qualitative or quantitative observation and investigates the activities of molecules and cells in physiological and pathological processes in vivo and in vitro with the use of specific molecular markers. Recently, imaging techniques in …
Recent data from our research group showed that null mutant strains of Salmonella enterica to genes encoding Naps (nucleoid-associated proteins) were attenuated for virulence and capable of inducing, in variable degrees, protection in the murine infection model. These results suggested an important role of different Naps in the bacterial virulence. During the development of our Postdoc pr…
| 15 / 7 | Completed research grants |
| 5 / 5 | Ongoing scholarships in Brazil |
| 33 / 18 | Completed scholarships in Brazil |
| 1 / 1 | Ongoing scholarships abroad |
| 3 / 3 | Completed scholarships abroad |
| 58 / 35 | All research grants and scholarships |
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