Glaucia Maria de Almeida

• Abstract

  Neurotropic viruses can cause central nervous system (CNS) diseases. About 30% of confirmed encephalitis cases are attributed to viral infections. Despite that, the molecular mechanisms and cellular alterations resulting from viruses infections in the human brain are still not well characterized. Murine models have been widely used to elucidate mechanisms associated with viral infections,…

  Tissue-molecular alterations associated with viral infections in adult human brain slice cultures, BP.DR
• Role of NETs in the pathogenesis of psoriasis, BP.TT

• Abstract

  Adult human brain organotypic cultures are a powerful method for studying cellular and molecular aspects of neuropathologies, as well as the effects of neuroprotective drugs. The main advantages of this method include maintaining the brain structure and its cellular connectivity. However, there is still a lack of studies that better characterize this model, not only to obtain more reliabl…

  Determination of neuronal function and oxidative metabolic profile in free-floating adult human brain-derived slice cultures, BP.MS

(Only some records are available in English at this moment)

• Abstract

  Brain slice cultures maintain the cytoarchitecture and cell connections present in brain tissue and have been widely applied in neuroscience research. In our laboratory, we have developed a method for culturing adult human brain tissue under free-floating conditions. In the past few years, we have applied this model to study cellular and molecular aspects associated with the brain pathoge…

  Subcellular localization of Oropouche virus in human brain slice cultures using super-resolution microscopy, BE.EP.DR