Abstract
Thyroid Hormone (TH) is critical to bone development and metabolism, however, the mechanisms through which TH regulates these processes are poorly understood. Recently, the Sympathetic Nervous System (SNS) was identified as a potent regulator of bone metabolism. A series of studies showed that the action of the SNS are mediated by Beta2-adrenoceptors (Beta2-AR) expressed in osteoblasts, a…