Leonardo holds a Bachelors degree in Pharmacy-Biochemistry (2019) from the School of Pharmaceutical Sciences of Araraquara, São Paulo State University Júlio de Mesquita Filho (FCFAr-UNESP). He obtained both his M.Sc. (2021) and Ph.D. (2025) in Pharmaceutical Sciences from FCFAr-UNESP, in the field of Pharmaceutical Technology, with research focused on the development of nanostructured systems for targeted drug delivery applied to the treatment of high-grade gliomas.During his masters degree, he developed functionalized lipid nanoparticles for the repurposing of docetaxel in glioblastoma treatment. During his Ph.D., he worked on the development of intranasal platforms based on functionalized lipid nanoparticles and hydrogels for the intranasal delivery of antitumor therapies to the central nervous system, including a doctoral research internship at NOVA Medical School (Lisbon, Portugal).He completed a postdoctoral fellowship (2025-2026) at the Mayo Clinic (Rochester, Minnesota, USA), focusing on the development of ionizable lipid nanoparticles for the delivery of RNA-based therapies targeting pediatric gliomas.He has experience in the development and physicochemical characterization of lipid-based nanosystems, formulation of semisolid systems for intranasal administration, molecular and functional evaluation of tumor biological responses in vitro, as well as orthotopic glioma models and in vivo biodistribution studies. He has also been actively involved in human resource training, contributing to the supervision and mentoring of more than 10 undergraduate research and undergraduate thesis students.Currently (2026), he is a postdoctoral researcher at IPHATEC (Innovative Pharmaceutical Technology Group) at FCFAr-UNESP, working on the development of novel drug delivery and gene therapy technologies for high-grade gliomas. (Source: Lattes Curriculum)
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Glioblastoma multiforme (GBM) is the most common and aggressive brain tumor of the central nervous system, characterized by rapid progression, therapeutic resistance, and poor overall survival. Temozolomide (TMZ), the standard chemotherapeutic agent, presents low brain bioavailability and resistance associated with the blood-brain barrier (BBB) and tumor heterogeneity. Restoration of the …
Glioblastoma Multiforme (GBM) is the most incident and most aggressive neoplasm of the Central Nervous System (CNS). Temozolamide (TMZ), the drug of choice for the treatment of GBM, has clinical efficacy, but treatment with this drug is associated with the development of resistance in more advanced stages of the disease, in addition to the fact that TMZ has physical and chemical limitatio…
Glioblastoma (GBM) is the most common primary malignant cancer of the central nervous system, responsible for about 4% of the deaths associated with tumors, characterizing itself as one of the most fatal cancers. Chemotherapy is widely used in treatment and docetaxel (DTX), Taxotere®, is a chemotherapeutic drug that has demonstrated efficacy in GBM treatment, inhibiting cell proliferation…
Vitamins are widely found in the plant kingdom, such as in plants and fruits. Ascorbic acid (AA) is one of these compounds and has a powerful antioxidant activity, in addition to functioning as a skin whitener, fighting free radicals and hyper-pigmentation of the skin. Another important representative compound is nicotinamide (Vitamin B3 or niacinamide), often used in cosmetics to be a pr…
Glioblastoma multiforme (GBM) is the most frequent and most aggressive Central Nervous System (CNS) cancer. Temozolomide (TMZ), the first-line drug for the treatment of GBM, has clinical efficacy, but treatment with this drug is associated with the development of resistance in more advanced stages of the disease, in addition to the fact that TMZ has physical-chemical limitations that hind…
Glioblastoma multiforme (GBM) is the most common primary malignant central nervous system cancer, responsible for about 4% of deaths associated with neoplasia, characterized as one of the most fatal human cancers. Chemotherapy is widely present in the treatment of glioblastoma and, among the commercial available drugs, docetaxel (DTX), Taxotere®, is a chemotherapy that has demonstrated ef…
Vitamins are widely found substances in nature, such as plants, fruits and other products. Ascorbic acid (AA) is one of these compounds and has a powerful antioxidant activity. In addition, it acts as a skin whitener, fighting free radicals and hyper-pigmentation of the skin. Another important representative compound is niacin (Vitamin B3 or niacotinamide), often used in cosmetics as a pr…
| 1 | Upcoming scholarships in Brazil |
| 3 | Completed scholarships in Brazil |
| 3 | Completed scholarships abroad |
| 7 | All Scholarships |
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