CV Lattes
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Universidade Presbiteriana Mackenzie (UPM). Centro de Ciências Biológicas e da Saúde (CCBS) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Farmacia from Universidade Federal de Pernambuco (1986), master's at Pharmacology from Universidade Federal de São Paulo (1992) and doctorate at Pharmacology from Universidade Federal de São Paulo (1997). Has experience in Physiology, focusing on Neorofisiology, acting on the following subjects: plantas medicinais, cecropia glazioui sneth, epilepsy, status epilepticus and epilepsia. (Source: Lattes Curriculum)
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The animal research facility of the Mackenzie Presbyterian University started its activities 7 years ago, houses rats and mice used in research in cardiovascular/renal physiology, toxicology, neurophysiology and behavioral neuroscience. Since its inception, 8 research projects, involving undergraduate and graduate students, yielded 85 manuscripts in scientific journal. In order to ensure…
Adult animals that have sustained neonatal lesions are increasingly considered useful models to study neurodevelopmental deficits underlying neuropsychiatric disorders such as schizophrenia and autism. Neonatal lesions are considered when ocurring between 8-10 days after birth, since this period corresponds to a full-term newborn. Status epilepticus (SE), an acute condition characterized …
Epilepsy is one of the most common neurological diseases, affecting over 70 million people worldwide. Growing evidence has shown that patients with temporal lobe epilepsy (TLE), frontal lobe epilepsy (FLE) and idiopathic epilepsies, even without the diagnosis of autism, present deficits in theory of mind (ToM) and in facial emotion recognition, especially for fear, which affect social af…
A single episode of neonatal seizure in rodents is a very promising model for the study of mechanisms underlying social impairment in Autism Spectrum Disorder (ASD), with animals exhibiting autistic-like behavior with no changes in cognition function. The social decision-making (SDM) network is formed by integration of two circuitries, social behavior network and mesolimbic reward system,…
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