Abstract
Disulfide reduction is a central aspect of life. In fact, the production of deoxyribonucleotides, components of DNA, involves thiol-disulfide exchange reactions. The thioredoxin system is composed of two proteins (Thioredoxin (Trx), and Thioredoxin Reductase (TrxR)), and NADPH and plays a central role in desoxyribunucleotides synthesis, besides acting as a reductant of antioxidant protein…