CV Lattes
ORCID
Google Scholar Citations
Universidade Estadual de Campinas (UNICAMP). Instituto de Química (IQ) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Mariana Celestina Frojuello Costa Bernstorff Damião in research grants and scholarships supported by FAPESP.
| News published in Agência FAPESP Newsletter about the researcher |
| More itemsLess items |
| TITULO |
| Articles published in other media outlets ( ): |
| More itemsLess items |
| VEICULO: TITULO (DATA) |
| VEICULO: TITULO (DATA) |
Among the technologies currently available, continuous flow chemistry can aid the synthesis of pharmaceutical actives by integrating multiple steps, and by direct scale up of reactions. In 2017 we developed an integrated flow synthesis for the rapid generation of 3-thio-1,2,4-triazoles from hydrazides and isothiocyanates. Lesinurad is a uric acid transporter protein (URAT1) inhibitor appr…
Chemical-induced "readthrough" of premature termination codons is an interesting approach to be explored by medicinal chemists for the treatment of genetic disorders caused by nonsense mutations. In an effort to develop new "readthrough" molecules, we intend to optimize pharmacodynamics and ADMET properties of previously synthesized analogs, and to design and generate new compounds based …
| 1 / 1 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 2 / 2 | All Scholarships |
| Associated processes | |