Abstract
The present study aims to evaluate in long-term (T0, T6 and T12) the enzymatic activity (zymography and in situ zymography), the bond strength, the collagen quality profile, and the nanoleakage in the adhesive interface of carious and non-carious teeth prepared with diamond burs or Er:YAG laser and restored using different adhesive techniques (self-etching and etching and washing). 120 no…