Yuli Thamires Magalhães

Universidade de São Paulo (USP). Instituto de Química (IQ) (Institutional affiliation from the last research proposal)
Birthplace: Brazil

Abstract
Glioblastoma (GBM) is the most incident and malignant glial tumor, and its high resistance to usual therapies contributes to its poor prognosis. Molecular analyzes have identified a high frequency of mutations in Rho GTPase pathway and actin cytoskeleton organization genes that seem to contribute to the maintenance of glioma stem cell (GSC) properties and to the infiltration of adjacent b…
Nuclear actin and Rho GTPases as targets for sensitization of radio and chemoresistant glioblastoma in Zebrafish and mice animal models, BP.PD
Abstract
Glioblastoma is the most common primary brain tumor, and despite the combination of surgery with radio and chemotherapy, the prognosis is still very poor. The increase in cell proliferation and migration of these tumors is directly related to their aggressiveness, which has recently been related to the Rho GTPases pathways. Functional evidence of the RhoA roles in gliomas has been demonst…
Investigating Rho GTPases pathways in the response of glioma cell lines to genotoxic stress, BP.DD

CV Lattes ORCID

2 / 2	Completed scholarships in Brazil

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