Abstract
Bone tissue is formed by some important cell types, such as: osteoblasts, osteoclasts and osteocytes. Osteoblasts are bone-forming cells, which synthesize and secrete collagen fibers and other organic components necessary for the formation of extracellular bone matrix, in particular collagen I, bone sialoprotein, osteocalcin and osteopontin. The osteogenesis process is divided into three …