CV Lattes
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Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. Escola Paulista de Medicina (EPM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Bachelor in Nursing (Federal University of Espírito Santo, 2015). Master (2017) and PhD (2022) in Science from the Graduate Program in Pharmacology at the Federal University of São Paulo (Department of Physiology - Cardiovascular Division). Dr. Milanez is currently studying the role of spinal circuitry in the establishment of sympathetic vasomotor activity in normal and hypertensive state. (Source: Lattes Curriculum)
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Sympathoexcitation contributes to the cardiorenal dysfunctions found in 2 kidneys, 1 clip (2K1C) hypertension, raising the need to investigate central changes in the model. Studies have reported changes in several pathways and neurotransmitters responsible for maintaining sympathetic activity in 2K1C animals. However, the impact of these central phenomena on effector functionality is stil…
The increase of the Sympathetic Nervous Activity (SNA), present in several models of hypertension, can be a determining factor for the genesis and maintenance of the disease. Experimental and clinical studies show that attenuation of elevated SNA may cause an improvement in the prognosis of hypertensive patients, especially those of renovascular origin. Elucidating the mechanisms underlyi…
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