Abstract
The production of nanoparticles, named by LDE, in our laboratory is already well standardized for some chemotherapeutics, such as paclitaxel, docetaxel, daunorubicin, etoposide and methotrexate. The modification of the chemical structure of the drug by esterification reactions is necessary to increase lipophilicity and ensure the incorporation of these drugs into the nanoparticles, thus o…