Abstract
Inflammasomes are macromolecular structures present in the cytoplasm of active immune cells that lead to the activation of caspases and, therefore, the elaboration of an inflammatory response. Activation of capase-1 results in the release of interleukins (IL-) 1B and 18 and induction of cell death by pyroptosis through maturation of cytosolic proteins of the gasdermin family (GSDM). Dereg…