Abstract
Depressed patients have volumetric reductions of the hippocampus, amygdala, prefrontal, Anterior Cingulate Cortices (ACC), and basal ganglia. Moreover, a metabolic decrease in dorsolateral prefrontal cortex (DLPFC) associated with increased activity in the cingulate cortex and limbic regions is observed. The white matter involved in implicit emotional regulation and reward processing neur…