CV Lattes
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Universidade de São Paulo (USP). Centro de Inovação da USP (INOVA) (Institutional affiliation from the last research proposal) Birthplace: Brazil
B. Pharm at the University of São Paulo (USP). Studied in Seoul National University in 2013-14, at the Chemical and Biological Engineering Department, as a visiting student through the Science Without Borders program. Obtained his PhD degree in Biochemistry in the Institute of Chemistry in the University of São Paulo (2017 - 2023) with the thesis: "How do antimicrobial peptides destroy membranes? A Molecular Dynamics perspective". During Sep/2020-Oct/2021, was part of Prof. Siewert Marrink's group, at the University of Groningen, Netherlands, in which using the MARTINI3 forcefield, simulated larger peptide/vesicle systems at higher concentrations. Currently, is a postdoc at INOVA-USP, in prof. Helder Nakaya's lab, developing methods to analyze the effects of mutations in cytokines that are relevant for the immune response of vaccines. (Source: Lattes Curriculum)
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This project aims to integrate genomic data of patients with Structural Biology, with the goal of predicting the efficacy of vacines at the individual level.Vaccines are essential in preventing infectious diseases and their effectiveness may vary between individuals due to genetic variations that affect the production of cytokines, signaling proteins involved in the immune response. Recen…
Cell Penetrating Peptides (CPP) invade eukaryotic cells without damaging the plasma membrane. TAT, a widely used CPP, is an intracellular carrier of drugs, proteins and DNA. The CPP penetration mechanism into cells, despite their increasing use, is controversial. Experimental and theoretical findings diverge; a group of authors propose that penetration depends on classic mechanisms such a…
Vaccines are essential in preventing infectious diseases and their effectiveness may vary between individuals due to genetic variations that affect the production of cytokines, signaling proteins involved in the immune response. Single nucleotide polymorphisms (SNPs) in cytokine genes can lead to an altered immune response. The use of Molecular Dynamics (MD) simulations has allowed the in…
Cationic membrane-active peptides (CMAP) are protagonists in many processes involving lipid membranes such as pore formation, vesicle fusion and rupture. Two CMAP groups stand out as potential novel drug or drug carrier candidates. Antimicrobial peptides (AMP), are a promising class of antibacterial agents and cell-penetrating peptides (CPP), are already candidates for drug-delivery. Many…
| 2 / 2 | Completed scholarships in Brazil |
| 1 / 1 | Ongoing scholarships abroad |
| 1 / 1 | Completed scholarships abroad |
| 4 / 4 | All Scholarships |
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