Abstract
In 2008, two isomeric tryptophan hydroperoxides (cis and trans WOOH) were characterized by our group as the main singlet oxygen tryptophan oxidation products. These peroxides break down into alcohols, formylkynurenine and kynurenine. In 2010, it was proposed that kynurenine is a relaxing endothelial factor that aids in controlling blood pressure. Under inflammatory conditions, the enzyme …