CV Lattes
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Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Bachelor of Biomedical Sciences from Universidade Anhembi Morumbi (UAM), graduated in 2020. During the undergraduate program, received research scholarships from CNPq and FAPESP, working in the field of Organ and System Physiology, with an emphasis on Renal Pathophysiology, at the Institute of Biomedical Sciences, University of São Paulo (ICB-USP). Currently pursuing a Ph.D. at the Renal Pathophysiology Laboratory in the Department of Physiology and Biophysics at ICB-USP, focusing on the role of Uromodulin in acute kidney injury and its progression to chronic kidney disease induced by crystal nephropathy, including the study of the disease's relapse phase.Experienced in experimental research, including laboratory animal handling, cell culture, and advanced molecular and protein analysis techniques, such as RNA extraction, real-time quantitative PCR (RT-qPCR), western blotting, immunohistochemistry, and immunofluorescence. Additionally, developing expertise in single-cell data analysis and proteomics, with a focus on bioinformatics applied to renal physiology. (Source: Lattes Curriculum)
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Crystalline nephropathy (crystals in the kidneys) is associated with Acute Kidney Injury and recurrence, but there are no data about the progression to the chronic phase. In addition, the appropriate treatment for this pathology is not known. Recent studies of our group have shown a significant decrease in the expression of Tamm-Horsfall Protein (THP) in the ascending thick limb of the lo…
The renal lithiasis or urinary stones is a frequent pathology in clinical practice with serious consequences depending on the duration and the frequency of recurrence of the insult. Although your clinical importance, little is known about the cellular mechanisms associated with acute kidney injury (AKI) due to the presence of kidney stones; the progression from the acute stage to chronic …
Acute kidney injury (AKI) is a major determinant of mortality and morbidity in hospitalized patients. Understanding the pathophysiology of AKI is essential for the development of therapy. Furthermore, AKI itself can lead to de novo chronic kidney disease (CKD) and progression towards end stage kidney disease. This application proposes to study the role of Tamm-Horsfall protein (THP) in re…
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