Abstract
Tuberculosis is a serious problem of public health because of the number of deaths caused by the disease and also by the number of resistant and multiresistant strains to all in use drugs. Among the key medicines used in the treatment of tuberculosis, isoniazid (INH) and pyrazinamide (PZA) are the first-line drugs, together withethambutol (EMB) and rifampicin (RIF). Recently, it has been …