CV Lattes
ORCID
Abstract
The IC fellow will work with the graduate and post-doctoral students of the thematic project under supervision. She will use the CRISPR-Cas9 system to induce mutations in the Aire gene, in mTEC cells line 3.10, the same mutations that are associated with the APS1 syndrome. We will make the selection of the mutations of the human Aire gene (SAND and PHD domains) to design the guide RNA (gR…