Abstract
Domestic dogs are the main urban reservoirs of Leishmania infantum, the causative agent of Visceral Leishmaniasis (VL) in the Americas. In VL endemic regions, the number of cases in humans is associated with the rate of canine infection. In CanL, sick dogs mount an inefficient cellular immune response (Th1) to fight the parasite concomitantly with an increase in the humoral immune respons…