Abstract
Necroptosis is a form of cell death regulated caspase-independent and is performed by receptor-interacting serine/threonine protein kinase 1(RIPK1), RIPK3 and mixed lineage kinase domain-like protein (MLKL). Recently, cancer therapy based on necroptosis has been proposed as an innovative strategy for antitumor treatment. In research on the cytotoxicity of drugs as antitumor therapy, cell …