Has experience in the area of #8203;#8203;Biochemistry, working with protein phosphatases in vitro and their oxidation. He is currently developing a project involving the redox and structural regulation of mitochondrial protein tyrosine phosphatase 1 (PTPMT1).. (Source: Lattes Curriculum)
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Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen classified by the WHO as a critical priority due to its high level of antibiotic resistance and its association with severe hospital-acquired infections. Its ability to adapt to hostile environments is closely linked to antimicrobial resistance and to its capacity to evade host defenses, such as oxidative stress generated by…
PTPMT1 is a mitochondrial protein tyrosine phosphatase and is involved in ATP synthesis and insulin secretion in pancreatic beta cells and in cardiolipin biosynthesis. PTPMT1 was the first protein phosphatase identified in mitochondria. Although PTPMT1 has been described as a PLIP (PTEN like protein), because it has a sequence in the PTP loop similar to that of PTEN, and because it has a …
Protein kinases and phosphatases are main actors in several signaling pathways and cellular functions, being responsible for the balance in the activation and production of molecules through the phosphorylation and dephosphorylation of their substrates. Different works have shown the importance of protein phosphatases located in sub-compartments of the mitochondria. Among them, DUSPs are …
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CV Lattes
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