Abstract
The human genome expresses about 100 functional tyrosine phosphatase enzymes (PTKs) that preferentially dephosphorylate tyrosine residues - but also tyrosine/serine or tyrosine/threonine - phosphorylated on protein substrates and other phospho-biomolecules. Some members of this class have increased protein expression levels in certain types of human tumors such as mammary, cervical, color…