Abstract
Congenital hypopituitarism (CH) leads to a hormonal deficiency that causes a clinical picture marked mainly by short stature and delayed growth velocity. Around 85% of patients with CH remain with the genetic etiology of this hormonal deficiency unknown. In the Endocrinology department at HCFMUSP, only 12% of patients with Congenital Hypopituitarism have a molecular diagnosis. The develop…