Fausto Bruno dos Reis Almeida in research grants and scholarships supported by FAPESP.
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Extracellular Vesicles (EVs) play an important role in export systems. They act as vehicles for the transference of complex cargoes with broad biological functions. These vesicles cross the fungal cell wall to reach the extracellular space and transport its major virulence factors contributing to fungal infection outcomes. Since we had the FAPESP young investigator grant phase 1, our grou…
Iron has a central position at the pathogen-host interface. Mammals have high affinity systems for iron sequestration from pathogens, and pathogen resistance to iron deprivation is a virulence factor. During iron deprivation, members of the Paracoccidioides complex, etiological agents of paracoccidioidomycosis disease induce iron acquisition systems, including siderophores production, hem…
Cryptococcus neoformans is the causative agent of cryptococcosis and a major pathogen for immunosuppressed individuals. C. neoformans represents a unique model in cell biology studies since it is the only eukaryotic pathogen with a polysaccharide capsule, furthermore produces vesicles containing its major virulence factor. These vesicles cross the cell wall to reach the extracellular spac…
Pathogenic fungi cause thousands of deaths each year. Extracellular vesicles (EVs) are structures formed by a lipid bilayer that carry in their interior proteins, nucleic acids, carbohydrates, pigments, and lipids. EVs are related to biofilm formation, stimuli of cytokine production, virulence transference, antifungal resistance, and cell-cell communication, contributing to pathogenicity …
Candida haemulonii is a multifaceted complex of Candida "non-albicans" species in evidence, classified as multi-resistant to available antibiotics in clinic. One of the species virulence strategies concerns in release extracellular vesicles (EVs) that could support the infection through bidirectional communication with host. Results about this EVs obtained by Nanoparticle Tracking Analysi…
Cancer represents a set of malignant neoplastic diseases and is among the main causes of death in the world. Between the affected biological systems, kidney Cancer represents 4.6% of the total number of Cancer diagnoses in the world in 2020, according to the WHO. Despite the low percentage, this figure represents more than 430,000 cases, 90% of which correspond to the Renal Cell Carcinoma…
(Only some records are available in English at this moment)
Candida haemulonii is an emerging and multidrug-resistant pathogen to the main antifungals available. The development of the infection is associated to the release of molecules on the environment, as occurs during the secretion of extracellular vesicles (EVs) that pass through the fungal cell wall to reach the extracellular space.Fungal EVs are composed of different biomolecules such as p…
Aspergillus fumigatus is the causative agent of Invasive Aspergillosis, a disease that presents a high mortality rate, and mainly affects immunocompromised individuals. The fungus has a global distribution and a large production of conidia, causing the human respiratory tract to be continuously exposed. Normally the destruction of conidia, and control of infection, is carried out by innat…
Aspergillus fumigatus is a fungus widely distributed in the environment and cited as the main cause of human infections in immunocompromised individuals. The infection success depends on the secretion of several molecules to the extracellular space. Extracellular vesicles (EVs) are produced by different organisms and cell types and can cross the cell wall to reach the extracellular space.…
(Only some records are available in English at this moment)
Cryptococcus neoformans is the causative agent of cryptococcosis and a major pathogen for immunosuppressed individuals. C. neoformans represents a unique model in cell biology studies because it is the only eukaryotic pathogen with a polysaccharide capsule, furthermore produces vesicles containing its major virulence factor. These vesicles cross the cell wall to reach the extracellular sp…
| 1 / 1 | Ongoing research grants |
| 7 / 2 | Completed research grants |
| 5 / 5 | Ongoing scholarships in Brazil |
| 9 / 9 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 24 / 19 | All research grants and scholarships |
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