CV Lattes
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Universidade de São Paulo (USP). Faculdade de Odontologia (FO) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduated in Dentistry at University of São Paulo (2001). Specialist in Endodontics at Hospital for Rehabilitation of Craniofacial Anomalies (2004). Master degree at University of São Paulo (Dental School of Bauru) at Endodontics. PhD at University of São Paulo in Oral Biology. Main research field: proinflammatory potential of oral fibroblasts. Additional research projects focusing on dental materials applied to Endodontics. (Source: Lattes Curriculum)
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Mineralized tissue resorption is a biological event present in challenging oral pathologies such as periodontal diseases, apical periodontitis and external root resorption. The role of mesenchymal cells at bone metabolism modulation is described, but not the role of apical papilla cells under this context, specially by means of osteoprotegerin (OPG) effect. The aim of this study is to inv…
The endodontic treatment of immature teeth is considered one of the greatest challenges of contemporary Endodontics. Despite the recent advances in this area of Dentistry, the molecular mechanisms involved with interruption of root formation resulting from dental caries or trauma are still unknown. Therefore, the aim of this study is to elucidate the role of inflammatory mediators in func…
The resorption of mineralized tissues is a biological event present in challenging oral pathologies such as periodontal disease, apical periodontitis, and external root resorption. The role of mesenchymal stem cells in modulating bone metabolism is already known, but not the role of apical papilla cells in this context, especially through the effect of osteoprotegerin (OPG). The aim of th…
Chemokines are cytokines that potentially attract distinct cell types trough chemotaxis. The CCL2 is the main chemokine involved at monocyte recruitment from peripheral blood to tissues; where, considering endodontic infections, these cells will differentiate into macrophages and osteoclasts. Based on the knowledge that stem cells of the apical papilla (SCAP) are an important source of CC…
Bone and root resorption are among the main responsible causes of tooth loss. Regenerative endodontic procedures have been recently proposed as an alternative for the treatment of external root resorption. Monocytes are the osteoclast precursor and they are considered key cells in this context. Stem cells of the apical papilla (SCAP) are in close contact with bone along root formation and…
The cells of apical papila (CPA) have direct influence in the root formation during dental development, acting as a source of dentin-synthesizing cells. If a pulpal pathological process is installed before the end of rhizogeneses, there is the possibility of pulpal necrosis and interruption of root formation. Although this cause/effect relationship is known, the molecular mechanisms invol…
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The apical papilla has an important role in root formation during dental development, acting as a source of stem cells that differentiate into the putative dentin-synthesizing cells, odontoblasts. Pulpal inflammation on immature teeth, resulting from caries or trauma, might lead to necrosis and the interruption of root formation. Among the inflammatory mediators potentially involved in th…
| 2 / 2 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 10 / 10 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 14 / 14 | All research grants and scholarships |
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