CV Lattes
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Universidade Estadual de Campinas (UNICAMP). Faculdade de Ciências Aplicadas (FCA) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Educação Física from Universidade Estadual Paulista Júlio de Mesquita Filho (2002), master's at Ciências da Motricidade from Universidade Estadual Paulista - Júlio de Mesquita Filho (2005) and doctorate at Clinical Medicine from Universidade Estadual de Campinas (2007). He is currently docente/pesquisador at Universidade Estadual Paulista - Júlio de Mesquita Filho and professor doutor ms-3 at Faculdade de Ciências Aplicadas da Unicamp- Limeira. Has experience in Physiology, focusing on Physiology of the Physical Effort, acting on the following subjects: biologia molecular, fisiologia do esforço, obesidade, exercício físico and fisiologia do exercício. (Source: Lattes Curriculum)
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Steatotic liver disease associated with metabolic dysfunction (DHEADM) is characterized by the accumulation of fat in the liver, with a close relationship with metabolic and cardiovascular disorders. It is currently the most common liver disease in the world, affecting around 25% to 30% of the population. The etiophysiology of DHEADM is complex, with obesity being a highly relevant risk f…
Recently, the World Health Organization classified Sarcopenia as a disease, which will allow the establishment of universal clinical guidelines for its diagnosis and treatment. In this sense, the rev-erb-alpha protein is a promising molecular target for the prevention and treatment of Sarcopenia, since it plays an essential role in the regulation of autophagy, mitochondrial content, oxida…
Overtraining syndrome is characterized by an imbalance between the recovery and training phases. Consequently, there may be a decline in performance and cognitive and behavioral disorders. Increases in pro-inflammatory cytokines are also notorious in this condition of over-training. The increase in interleukin-6 (IL-6) has been linked to the development of depressive signs. Intriguingly, …
Obesity and diabetes are two major serious public health problems worldwide, with significant economic and social impact and consequent burden of morbidity and mortality in the population. The main risk factors for the development of obesity and diabetes are physical inactivity and unbalanced nutrition. Advanced age and family history complete this list of the most significant risk factor…
During the process of senescence, some factors such as the physiological function declining, the increased high fat food intake, and the inactivity are related with impairments in the hepatic metabolism leading to hepatic fat accumulation, also known as nonalcoholic fatty liver disease (NAFLD). Once the NAFLD is presented, there is a risk for non-alcoholic steatohepatitis (NASH) developme…
(Only some records are available in English at this moment)
Menopause marks the end of female reproductive capacity and is characterized by a drop in the production of estrogen and progesterone. This hormonal decline results in a variety of symptoms, such as weight gain, insulin resistance, and an increased risk of metabolic diseases, including steatotic liver disease associated with metabolic dysfunction (MASLD). Hepatic metabolism is affected by…
There is evidence that a high-fat diet and sleep deprivation are important risk factors for increased body adiposity and sarcopenia. On the other hand, time-restricted feeding (TRF) and physical exercise have been strategies applied to combat these illnesses. However, it still needs to be explored whether TRA associated with aerobic and resistance physical training (combined training) may…
Obesity is a major health issue, with diverse consequences including the exacerbated deposition of fat in the liver and reduction in skeletal muscle mass, which consequently contributes to the development of metabolic disorders such as hyperglycemia and the emergence of cardiovascular diseases, type 2 diabetes and non-alcoholic fatty liver disease (NAFLD). In this scenario, multiple facto…
Non-alcoholic fatty liver disease (NAFLD), a condition characterized by the accumulation of fat in the liver, is estimated to be the most common liver disease worldwide. Being that obesity is an important risk factor and contributor to the development of NAFLD and, therefore, weight reduction can improve this disease. Previous studies in preclinical models of diet-induced obesity and fatt…
Increased body adiposity is associated with hyperglycemia, contributing to an increased risk of developing type 2 diabetes mellitus (type 2 DM) in the obese population. In addition, studies show that high blood glucose levels and impaired insulin signaling are related to an exacerbated increase in hepatic glucose production. There is evidence that Krüppel-like transcription factor 15(KLF1…
Athletes are usually exposed to strenuous training phases and, when the balance between training and recovery is not respected, they can develop the Overtraining Syndrome through excessive training. This phenomenon is characterized by a sustained physical performance decrement, and they generally present psychological disorders, such as anxiety and depression. Excessive training induces c…
(Only some records are available in English at this moment)
Obesity is a chronic multifactorial disease characterized by excessive body fat accumulation, and its increasing prevalence has become a serious public health issue. In addition to being associated with metabolic disorders such as dyslipidemia, arterial hypertension, and glucose intolerance, obesity is a risk factor for insulin resistance and type 2 diabetes. Insulin resistance, triggered…
Fatty liver disease associated with metabolic dysfunction (MAFLD) is a disease with increasing global prevalence and requires urgent strategies. It is known that activation of the Notch pathway in hepatocytes is associated with MAFLD. Activation of the Notch1 protein in hepatocytes increases triglyceride synthesis intracellularly, stabilizing the mechanistic target of rapamycin complex 1 …
Athletes often undergo intense physical training to enhance performance, but maintaining a balance between stimulus and recovery is crucial. Disruption of this balance can lead to adverse outcomes, including a proinflammatory state and major depressive disorder (MDD) associated with exhaustive training, or overtraining. Recent evidence suggests a complex interaction between proinflammator…
Over the past decade, the epidemiology of steatotic liver disease associated with metabolic dysfunction (MASLD) has grown exponentially. Notch signaling pathways have been implicated in the pathogenesis of this disease. The Notch pathway is an intercellular signaling cascade vital in multiple cellular functions. on metabolism, including body weight, energy metabolism, blood lipid composit…
Obesity is a serious public health problem characterized by excessive accumulation of body fat, involving a wide variety of factors (genetic, metabolic, social, behavioral, psychological, and environmental), with worldwide scope and rates that have almost doubled in the last 30 years (1,2). The meta-inflammation present in obesity induces impairments in insulin signaling and action, with …
The current climate crisis has been sharply exerting global pressure to alter patterns of action and accelerate profound changes in pursuit of sustainable urban systems. Within this scenario, the community of scholars in sustainability transitions has sought approaches that enable path-deviating advances in socio-technical systems, especially at the urban scale. However, understanding and…
(Only some records are available in English at this moment)
| 2 / 2 | Ongoing grants |
| 12 / 10 | Completed research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 20 / 19 | Completed scholarships in Brazil |
| 3 / 3 | Ongoing scholarships abroad |
| 8 / 8 | Completed scholarships abroad |
| 48 / 45 | All research grants and scholarships |
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