Abstract
Chondrosarcomas (CS) are rare and heterogeneous tumors, characterized by the formation of hyaline cartilaginous neoplastic tissue, and represent around 30% of malignant bone tumors. Around 90% of CS are conventional and the other 10% are rarer subtypes. The most common point mutations in these tumors occur in the IDH1 and IDH2 genes, present in approximately 52-59% of cases, and in the TE…