Abstract
Antibiotic resistance in bacteria is one of the greatest threats to global public health, and the spread of resistance genes, such as those encoding ¿-lactamases, has complicated the treatment of severe infections. Among these enzymes, CMY-2, an AmpC-type ¿-lactamase present in plasmids, has stood out for conferring resistance to broad-spectrum cephalosporins and other ¿-lactams. Recently…