Abstract
Gastrointestinal tract tumors (GIT) are in world an important part of cancer cases. In 2020, colorectal cancer was responsible for more than 1.9 million new cases and 935 thousand deaths, representing approximately one in ten of new cases. Fluoropyrimidines and irinotecan are drugs commonly used for treatment of GIT, and diarrhea is one of their main side effect. This is a limiting event …