CV Lattes
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Ministério da Ciência, Tecnologia e Inovação (Brasil). Centro Nacional de Pesquisa em Energia e Materiais (CNPEM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Dr. Renato Sousa Lima is a researcher at the National Nanotechnology Laboratory (LNNano/CNPEM), Coordinator of the Diagnostic Subprogram of the CNPEM Health PD Program, and Visiting Professor in the following Postgraduate Programs: IQ/UNICAMP, IQSC/USP, and NMA/UFABC. He has a bachelors degree in Industrial Chemistry from UFPB (2003-2008), a master's degree (2008-2010) and a doctorate (2010-2013) in Sciences from IQSC/USP, and a post-doctorate from UNICAMP (2014-2015) and Clemson University/USA (2023-2024). Throughout his postgraduate studies, he worked in the area of Chemistry, with an emphasis on electrochemistry, micro/nanofabrication, and microfluidics for chemical analysis. He leads a research group that seeks to address the following problem: performing accessible, easy-to-implement (in laboratories or at the point of need), high-throughput, and accurate chemical analyses in the areas of environment and health. To this end, the group's mission is to deploy solutions in devices for generating electrochemical sensors carrying the attributes mentioned above. His actuation areas are (i) device fabrication (micro/nanofabrication and alternative methods), (ii) use of nano/materials (such as thin films and nanostructured microstructures), (iii) investigation of surface phenomena at the nanoscale, (iv) microfluidics, and (v) machine learning. The researcher has completed the supervision of 4 master's and 2 doctoral degrees, is a reviewer for several journals, and is the author of more than 60 scientific articles in journals with strict editorial policies, such as Analytical Chemistry, ACS Sensors, ACS Applied Materials Interfaces, ACS Nano, and Advanced Healthcare Materials. (Source: Lattes Curriculum)
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The preclinical phase is critical for the success of drug development, lasting 5 to 7 years and over which the viability of cell cultures (number of viable cells) is determined to assess the in vivo efficacy of drugs. In these drug susceptibility tests, viability analysis methods are usually laborious, time-consuming, and invasive. In this sense, electrochemical devices are a promising al…
This Project addresses an approach created at Microfabrication Laboratory in 2014. Called microemulsification-based method (MEC), it employs for the first time the thermodynamic stabilization of dispersions (microemulsification) to perform analytical determinations. The generation of nanodroplets in stable dispersions of microemulsions (MEs; transparent) allows complex chemical determinat…
In vitro tests of cell susceptibility to chemotherapy are important for precision oncology, as they support clinical decisions regarding the safest and most effective chemotherapy strategy in a precise and personalized manner, contributing to increasing patient survival. In this case, the in vitro assessment of the effect of drugs is done by analyzing the viability (number of live cells) …
The pharmaceutical industry faces critical challenges in developing successful pharmaceutical drugs. This process takes 10 to 15 years and requires around US$1 billion. Furthermore, more than 95% of drug candidates fail to get approval from regulatory agencies. On average, the preclinical drug screening takes from 5 to 7 years. Along this journey, the candidates are challenged with cell c…
Oral squamous cell carcinoma (OSCC) is the most common type of head and neck cancer and has a propensity for lymph node metastases, which decreases the 5-year survival rate of patients by up to 50%. The diagnosis of this carcinoma is made through tissue biopsy, a laborious, expensive, invasive method that does not allow the detection of lymph node metastasis in its initial stage. Thus, th…
(Only some records are available in English at this moment)
This project aims to develop label-free electrochemical biosensors (LEBs) with the potential to facilitate rapid and cost-effective disease diagnosis in various clinical settings, including laboratories, hospitals, and point-of-care scenarios. To achieve this objective, we intend to fabricate devices that fulfill two critical criteria: (i) real-world applicability at an economically viabl…
The poor reproducibility of nanomaterials synthesis and functionalization is the greatest challenge facing the development of nanotechnologies. Therefore, by taking up the increasing demand for scaling up the production of these materials and the impact of their surface chemistry on the applications, the construction of simple, fast, and portable sensors for ex-situ and in-situ quality co…
In this project, we describe the development of ultrasensitive point-of-care electrochemical methods by incorporating nanostructured concentric electrodes - with vertically aligned single-walled carbon nanotubes - in microfluidic devices. The potential effect of this new assembly was evaluated using contactless conductivity detection (concentric electrodes) and voltammetric techniques (na…
(Only some records are available in English at this moment)
The urgent need for rapid, accessible, and accurate methods for antibiotic susceptibility testing (AST) in bacteria drives this project. According to the World Health Organization (WHO), antimicrobial resistance (AMR) is one of the greatest global public health challenges, driven by mechanisms such as intrinsic resistance, acquired resistance, genetic changes. This process is part of the …
The antimicrobial resistance (AMR) has been recently defined by the World Health Organization as one of the top 10 global public health threats facing humanity. AMR not only makes infections harder to be treated, but also it has been found out to increase the illness severity and hasten the spread of infections in hospitals and in the community. Antimicrobial susceptibility testing (AST) …
| 1 / 1 | Ongoing grants |
| 1 / 1 | Completed research grants |
| 4 / 4 | Ongoing scholarships in Brazil |
| 5 / 4 | Completed scholarships in Brazil |
| 1 / 1 | Ongoing scholarships abroad |
| 1 / 1 | Completed scholarships abroad |
| 13 / 12 | All research grants and scholarships |
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