CV Lattes
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Secretaria de Desenvolvimento Econômico (São Paulo - Estado). Faculdade de Medicina de Marília (FAMEMA) (Institutional affiliation from the last research proposal) Birthplace: Brazil
He has a degree in Biomedicine from the University of Marília (2007), a Master's degree in Oral Biology from the Sagrado Coração University (2009) and a PhD in Science: Morphology/Genetics from the Federal University of São Paulo (2012). He is currently a Professor at the Faculty of Medicine of Marília (FAMEMA), head of the Cellular and Molecular Biology discipline, in addition to being a Permanent Professor of the Postgraduate course at the Faculty of Medicine of Marília (Health and Aging). He is also a Professor at the University Center of Faculdades Integradas de Ourinhos. At FAMEMA, the Problem Construction Group (Active Methodology - PBL) and the NDE of the Nursing Course are members. At the Centro Universitário de Ourinhos he is Coordinator of the Research and Extension Center and the NDE of the Biomedicine Course. Develops research in an interdisciplinary area with an emphasis on Cellular and Molecular Biology, focusing on the analysis of gene and protein expression - mRNA and microRNAs, detection of polymorphisms and genetic profile of Helicobacter pylori, working mainly on the topics: Alzheimer's Disease, Gastric Cancer, Helicobacter pylori, Inflammation and Apoptosis. (Source: Lattes Curriculum)
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The persistent infection of gastric mucosa by the Helicobacter pylori (H. pylori) causes a chronic inflammation and creates a favorable microenvironment to the onset of atrophic gastritis with a possible progression to gastric cancer. The stimulus to the immune and inflammatory response leads to epithelial changes which stimulate the apoptosis, and the imbalance between the inflammatory p…
The Institutional Research Infrastructure Cost Share will be used to improve the infrastructure of multidisciplinary research laboratories at the Universidade do Sagrado Coração. Acquisitions of equipment will be made to optimize Laboratories and the dynamics of the researchers.This amount will be used to purchase: Twenty-eight (28) Box forrodents; One (01) euthanasia chambers; One (01) …
The persistent infection of the gastric mucosa by Helicobacter pylori (H. pylori), promotes a chronic inflammation, providing a microenvironment favorable for the appearance of atrophic gastritis with possible progression to gastric cancer. The stimulation to the immune and inflammatory response favors epithelial changes; which in turn stimulate apoptosis, the imbalance between the inflam…
The Institutional Research Infrastructure Cost Share will be used to improve the infrastructure of multidisciplinary research laboratories at the Universidade do Sagrado Coração. Acquisitions of equipment will be made to optimize Laboratories and thedynamics of the researchers.This amount will be used to purchase the Video Conference System (R $ 2,890.00), (Logitech C920 Webcam, Digipod T…
(Only some records are available in English at this moment)
Helicobacter pylori is a microaerophilic, Gram-negative, flagellated, and spiral-shaped bacterium widely associated with gastric pathologies by creating an environment of chronic inflammation in the stomach lining. Its asymptomatic infection hinders early diagnosis and allows the progression of clinical complications. The stimulation of an exacerbated immune response disrupts cellular hom…
The infection of the gastric mucosa by Helicobacter pylori (H. pylori) promotes a chronic inflammation, providing a microenvironment favorable for the appearance of atrophic gastritis with progression to gastric cancer. The increase in IL-6 synthesis, as well as the presence of the polymorphisms -174 (G/C) (rs1800795), -572 (C/G) (rs1800796) and -597 (G/A) (rs1800797), appear to be associ…
Interleukin-10 (IL-10) is an anti-inflammatory and immunosuppressive cytokine produced by several cell types, including macrophages, dendritic cells and various T-cell subgroups. This cytokine is released with the aim of modulating the synthesis of pro-inflammatory cytokines ensuring that no exacerbated inflammation occurs. However, polymorphisms in the IL-10 promoter region may be relate…
The Tumor Necrosis Factor is a proinflammatory cytokine, mainly synthesized by macrophages and monocytes, and is the main stimulus for the production thereof, the lipopolysaccharides that are the membrane of Gram-negative bacteria. The Helicobacter pylori is a gram-negative bacterium that colonizes the mucosa of the stomach and is responsible for various gastroduodenal diseases such as ga…
(Only some records are available in English at this moment)
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| 7 / 7 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 9 / 9 | Completed scholarships in Brazil |
| 18 / 18 | All research grants and scholarships |
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