Abstract
Parkinson's Disease (PD) is a neurodegenerative disease that involves loss of neurons in the substantia nigra, leading to effects such as bradykinesia, akinesia, resting tremor, muscular rigidity, gait and postural instability, and cognitive disabilities later. An animal model widely used to study the DP is the model that uses the direct administration of 6-OH-dopamine (6-OHDA) in the med…