José Antonio Silva Junior
CV Lattes
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Universidade Nove de Julho (UNINOVE). Campus Vergueiro (Institutional affiliation for the last research proposal) Birthplace: Brazil
graduate at Pharmacy from Universidade Federal de Ouro Preto (1991), master's at Morphology from Universidade de São Paulo (1997) and Ph.D. at Biochemistry from Universidade Federal de São Paulo (2001). Has experience in Byophysics, focusing on Molecular Biophysics, acting on the following subjects: biologia molecular, inflamação, patologia, cininas and fisioterapia. (Source: Lattes Curriculum)
- Comparative mRNA and microRNA profiling during acute myocardial infarction induced by coronary occlusion and ablation radio-frequency currents, PUB.ART
Abstract
The ligation of the left anterior descending coronary artery is the most commonly used experimental model to induce myocardial infarction (MI) in rodents. A high mortality in the acute phase and the heterogeneity of the size of the MI obtained are drawbacks recognized in this model. In an attempt to solve the problem, our group recently developed a new MI experimental model which is bas...
- The pathophysiology of congestive heart failure: from the organ to tile molecules, AP.TEM
Abstract
The project aims at investigating the relevant aspects involved in the pathophysiology of Congestive Heart Failure (CHF). Seven subprojects will be part of the CHF experimental model induced in rats after myocardial necrosis. As a whole, the project includes: three subprojects to investigate the effects of prolonged use of digitoxin after myocardial infarction. One of them will conduct ...
- Apoptosis in tumors, AP.TEM
Abstract
Apoptosis is the mechanism of cell death which promotes the removal of cells in normal tissue and is fundamental during development. In tumors, it can be the result of extra cellular stimulus or of characteristics intrinsic to the cells, depending on the expression of oncogenes. Alterations in genes which codify endonuclear caspases, receptors of cell death and mitochondrial proteins ar...
- Gene expression characterization of signal transduction pathways in the remote myocardium after infarction induced by left ventricular ablation and coronary artery occlusion in rats, BP.DR
Abstract
The ligation of anterior descending coronary artery is the most widely used experimental model to induce myocardial infarction (MI) in rodents. The high mortality in the acute phase and the heterogeneity of the size of MI obtained are recognized drawbacks in this model. In an attempt to solve the problem, recently was developed a new experimental model of MI in rats based on the applica...
| 4 / 3 | Completed research grants |
| 3 / 1 | Completed scholarships in Brazil |
| 1 / 0 | Completed scholarships abroad |
| 8 / 4 | All research grants and scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
SANTANA, EDUARDO T.; FELICIANO, REGIANE DOS SANTOS; SERRA, ANDREY J.; BRIGIDIO, EDUARDO; ANTONIO, EDNEI L.; TUCCI, PAULO J. F.; NATHANSON, LUBOV; MORRIS, MARIANA; SILVA, JR., JOSE A.. Comparative mRNA and MicroRNA Profiling during Acute Myocardial Infarction Induced by Coronary Occlusion and Ablation Radio-Frequency Currents. FRONTIERS IN PHYSIOLOGY, v. 7, NOV 25 2016. Web of Science Citations: 2. (12/15808-0, 09/54225-8, 15/11028-9)